Isotopically Labeled Compounds
Cambridge Isotope Laboratories GLYME (1,2-DIMETHOXYETHANE) (D10, 99%), 5 G, 107975-86-0
GLYME (1,2-DIMETHOXYETHANE) (D10, 99%), 5 G, 107975-86-0
Cambridge Isotope Laboratories 7-Methylguanine (methyl-D3 98%) 0 01 g
7-Methylguanine (methyl-D3 98%) 0 01 g
Cambridge Isotope Laboratories Di-N-Butyl phthalate (ring-D4 98%) 0 1 g
Di-N-Butyl phthalate (ring-D4 98%) 0 1 g
Medchemexpress LLC Anserine-d4 | 1201658-81-2 | 99.4% | 244.28 | 1 MG
Anserine-d4 is a deuterium-labeled version of Anserine, which is a naturally occurring, orally active Histidine-containing dipeptide found in the skeletal muscle of vertebrates. Anserine acts as a biochemical buffer, chelator, antioxidant, and anti-glycation agent, and is known to improve memory functions.
- Deuterium-labeled compound for research applications.
- Functions as a biochemical buffer.
- Acts as a chelator.
- Serves as an antioxidant.
- Exhibits anti-glycation properties.
- May improve memory functions.
Medchemexpress LLC L-Theanine-d5 (L-Glutamic Acid γ-ethyl amide-d5) | 1217451-85-8 | C7H9D5N2O3 | 1 MG
L-Theanine-d5 is a deuterium-labeled version of L-Theanine, a non-protein amino acid found in green tea leaves. It operates by blocking the binding of L-glutamic acid to glutamate receptors in the brain, exhibiting neuroprotective and anti-oxidative activities. Oral intake can induce anti-stress effects by inhibiting cortical neuron excitation.
- Can be used as a tracer
- Serves as an internal standard for quantitative analysis
- Suitable for techniques such as NMR, GC-MS, or LC-MS
- Deuterium incorporation assists in quantitation during drug development
Medchemexpress LLC Glyburide-d11 | 1189985-02-1 | C23H17D11ClN3O5S | 1 MG
Glyburide-d11 is the deuterium labeled Glibenclamide, an orally active ATP-sensitive K+ channel (KATP) inhibitor. It is used for research related to diabetes and obesity. Glyburide-d11 inhibits P-glycoprotein, directly binds and blocks the SUR1 subunits of KATP, and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR). It interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability and can induce autophagy.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Inhibits P-glycoprotein
- Blocks SUR1 subunits of KATP
- Inhibits cystic fibrosis transmembrane conductance regulator protein (CFTR)
- Interferes with mitochondrial bioenergetics
- Can induce autophagy
![Medchemexpress LLC L-Alanine-3,3,3-d3, N-[(9H-fluoren-9-ylmethoxy)carbonyl]- | 225101-67-7 | 99.4% | 314.35 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000366938-logo.png-250.jpg){kind=logo}
Medchemexpress LLC L-Alanine-3,3,3-d3, N-[(9H-fluoren-9-ylmethoxy)carbonyl]- | 225101-67-7 | 99.4% | 314.35 | 10 MG
Fmoc-Ala-OH-3,3,3-d3 is the deuterium labeled Fmoc-Ala-OH-3,3,3 and is intended for research use only. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, primarily as tracers for quantitation during the drug development process. Deuteration has gained attention due to its potential to influence the pharmacokinetic and metabolic profiles of drugs.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Isovaleric acid-13C | 87994-84-1 | MFCD00084022 | 99.0% | 103.12 | 50 MG
Isovaleric acid-13C is a stable isotope-labeled version of Isovaleric acid, a naturally occurring fatty acid. It is commonly used in research as a tracer and as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS. This compound aids in studying metabolic pathways and drug pharmacokinetics.
- Used as a tracer in various research applications.
- Functions as an internal standard for quantitative analysis.
- Beneficial for metabolic studies.
- Helps in understanding drug pharmacokinetics.
- Supports analytical methods like NMR, GC-MS, and LC-MS.
Medchemexpress LLC Isovaleric acid-d7 | 1219805-32-9 | 99.5% | 109.17 | 50 MG
Isovaleric acid-d7 is the deuterium labeled Isovaleric acid. Isovaleric acid is a natural fatty acid known to affect neonatal death and possible Jamaican vomiting sickness in humans. It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer.
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration can affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Tolcapone-d4 (ro 40-7592-d4) | 1246816-93-2 | 99.1% | 277.27 | 1 MG
Tolcapone-d4 (Ro 40-7592-d4) is the deuterium labeled Tolcapone (HY-17406). Tolcapone (Ro 40-7592) is a selective, potent and orally active COMT inhibitor with an IC50 of 773 nM. Tolcapone can inhibit α-syn and Aβ42 oligomerization and fibrillogenesis. Tolcapone can cause oxidative stress and induce cancer cells apoptosis and ROS production. Tolcapone can be used for the researches of cancer and neurological disease, such as Parkinson disease and neuroblastoma.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC 1-Tetradecanol-d2 | 169398-02-1 | 216.40 | 10 MG
1-Tetradecanol-d2 is the deuterium labeled 1-Tetradecanol. 1-Tetradecanol, isolated from Myristica fragrans, is a straight-chain saturated fatty alcohol that possesses antibacterial and anti-inflammatory (periodontitis) activity. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process.
Medchemexpress LLC Paraxanthine-d6 | 117490-41-2 | 98.9% | 186.20 g/mol | C7H2D6N4O2 | 500 UG
Paraxanthine-d6 is the deuterium-labeled analogue of paraxanthine supplied as a stable-isotope internal standard for analytical and research applications. It is intended for research use only and is commonly used in LC-MS and GC-MS quantification of caffeine metabolites and related metabolic and pharmacokinetic studies.
- Deuterium-labeled internal standard for LC-MS and GC-MS.
- High isotopic enrichment to support accurate quantification.
- Suitable for pharmacokinetic and metabolic studies of caffeine and its metabolites.
- Available in small analytical pack sizes for trace-level assays.
- For research use only; not for human or clinical use.
Cambridge Isotope Laboratories 2-HYDROXYBENZOIC ACID (SALICYLIC ACID) (D6, 97%), 0.25 G, 285979-87-5
2-HYDROXYBENZOIC ACID (SALICYLIC ACID) (D6, 97%), 0.25 G, 285979-87-5
Medchemexpress LLC p-Tolualdehyde-d7 | 1219805-23-8 | 98.2% | 127.19 | 100 MG
p-Tolualdehyde-d7 is the deuterium-labeled p-Tolualdehyde. It is an active small molecule that can be used as a drug intermediate. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Stable heavy isotopes like deuterium have been incorporated into drug molecules for quantitation during drug development and have the potential to affect pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled compound
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Ciprofloxacin-d8 (hydrochloride) | 1216659-54-9 | 98.8% | 2.5 MG
Ciprofloxacin-d8 (hydrochloride) is the deuterium labeled Ciprofloxacin. Ciprofloxacin (Bay-09867) hydrochloride is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.